李诗颖
博士，在站博士后
- 教育/工作经历：
2017.09 - 2021.08香港理工大学，应用生物与化学技术，博士 2015.08-2016.10 香港理工大学，生物医学工程，硕士 2011.10-2014.10 英国帝国理工学院，化学，学士
- 主要研究方向：
研发高清晰分子成像平台，更好地理解肿瘤的异质性，疾病的早期诊断，监测化学药物和光热治疗反应；构建新型化疗-光热联合治疗的纳米诊疗体系实现对癌症的精准治疗，增加整体治疗的选择性，在癌症治疗中具有广阔的应用前景。
- 研究关键词（中英文）
代表性成果：
1. Shiying Li, Kwok-Ho Lui, Wing-Sum Lau, Yan-Juan Gu*, Liang-ting Lin*, and Wing-Tak Wong*. MSOT- Guided Nanotheranostics for Synergistic Mild Photothermal Therapy and Chemotherapy to Boost Necroptosis/Apoptosis. ACS Applied Materials & Interfaces, 2022, 14(29): 33712–33725.
2. Lanqing Li‡, Shiying Li‡. Current Strategies of Photoacoustic Imaging Assisted Cancer Theragnostics toward Clinical Studies. ACS Photonics, 2022, 9(8): 2555-2578.
3. Shiying Li‡, Kwok-Ho Lui‡, Tik-Hung Tsoi, Yan-Juan Gu*, Wing-Tak Wong*. pH-Responsive Targeted Gold Nanoparticles for in vivo Photoacoustic Imaging of Tumor Microenvironment. Nanoscale Advances, 2019, 1: 554-564.
4. Shiying Li, Kwok-Ho Lui, Yan-Juan Gu*, Wing-Tak Wong*. PH-Triggered Poly (ethylene glycol)-Poly(lactic acid/glycolic acid)/Croconaine Nanoparticles-Assisted Multiplexed Photoacoustic Imaging and Enhanced Photothermal Cancer Therapy. ACS Applied Bio Materials, 4 (5): 4152-4164.
5. Kwok Ho Lui‡, Shiying Li‡, Wai-Sum Lo, Yanjuan Gu*, Wing-Tak Wong*. In Vivo Photoacoustic Imaging for Monitoring Treatment Outcome of Corneal Neovascularization with Metformin. Biomedical Optics Express, 2021, 12: 3597-3060.
6. Cheng Liu‡, Shiying Li‡, Yanjuan Gu, Huahua Xiong, Wing-Tak Wong*, Sun, Lei*. Multispectral Photoacoustic Imaging of Tumor Protease Activity with a Gold Nanocage-Based Activatable Probe. Molecular Imaging and Biology, 2018, 20: 919-929.
7. Xueyang Fang, Kwok-Ho Lui, Shiying Li, Wai-Sum Lo, Xin Li, Yanjuan Gu*, Wing-Tak Wong*. Multifunctional Nanotheranostic Gold Nanocage/Selenium Core-Shell for PAI-Guided Chemo-Photothermal Synergistic Therapy in vivo. International Journal of Nanomedicine, 2020, 15: 10271-10284.
8. Xin Li, Xueyang Fang, Shiying Li, Kwok-Ho Lui, Wai-Sum Lo, Yanjuan Gu*, Wing-Tak Wong*. Nitroreductase-Induced Aggregation of Gold Nanoparticles for “Off–On” Photoacoustic Imaging of Tumor Hypoxia. Journal of Biomedical Nanotechnology 17(11): 2186-2197.
9. Baojie Gong, Jianxin Tang, Xiaoxiao Jiang, Zhe Zhang, Shiying Li, Hongjun Jin, Liming Nie*, and Guojia Huang*. In situ fluorescence-photoacoustic measurement of the changes of brown adipose tissue in mice under hindlimb unloading. Journal of Applied Physiology, 2023.