曾俊伟

哲学博士

教育/工作经历:
大学及硕士分别毕业于佛山科学技术学院及中国农业大学,博士毕业于田纳西大学(Knoxville)微生物系。在艾默里(Emory)大学和哈佛(Harvard)大学/BIDMC接受博士后训练,后任哈佛医学院讲师。于2021年底入职广东省人民医院。
主要研究方向:
专注糖免疫学,着重探究O型糖在免疫介导的生理和病理过程中的作用及机制,并针对慢性病中的异常O型糖结构开发相应抗体。已初步揭示O型糖在B细胞免疫及自身免疫中的功能调控作用。以第一作者和通讯作者(含共同)在Science Advances, Nature Communications, Journal of Immunology 等刊物发表多篇研究论文。
研究关键词(中英文)

代表性论文:

(1) Florian Erger; Rajindra P Aryal; Björn Reusch; Yasuyuki Matsumoto; Robert Meyer; Junwei Zeng; Cordula Knopp; Maxence Noel; Lukas Muerner; Andrea Wenzel; Stefan Kohl; Nikolai Tschernoster; Gunter Rappl; Isabelle Rouvet; Jutta Schröder-Braunstein; Felix S Seibert; Holger Thiele; Martin G Häusler; Lutz T Weber; Maike Büttner-Herold; Miriam Elbracht; Sandra F Cummings; Janine Altmüller; Sandra Habbig; Richard D Cummings; Bodo B Beck; Germline C1GALT1C1 mutation causes a multisystem chaperonopathy, Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (22): e2211087120 

(2) Junwei Zeng*; Rajindra P Aryal; Kathrin Stavenhagen; Chi Luo; Renyan Liu; Xiaohui Wang; Jiaxuan Chen; Hao Li; Yasuyuki Matsumoto; Yingchun Wang; Jianmei Wang; Tongzhong Ju; Richard D. Cummings* ; Cosmc deficiency causes spontaneous autoimmunity by breaking B cell tolerance,  Science Advances , 20217 (41): eabg9118 (*co-corresponding author)

(3) Junwei Zeng; Mahmoud Eljalby; Rajindra P. Aryal; Sylvain Lehoux; Kathrin Stavenhagen; Matthew R. Kudelka; Yingchun Wang; Jianmei Wang; Tongzhong Ju; Ulrich H. von Andrian; Richard D. Cummings ; Cosmc controls B cell homing,  Nature Communications , 2020, 11(1), 3990

(4) Junwei Zeng*; Rongjuan Mi*; Yingchun Wang; Yujing Li; Li Lin; Bing Yao; Lina Song; Irma van Die; Arlene B Chapman; Richard D Cummings; Peng Jin; Tongzhong Ju ; Promoters of Human Cosmc and T-synthase Genes Are Similar in Structure, Yet Different in Epigenetic Regulation,  Journal of Biological Chemistry , 2015, 290(31): 19018-19033. (*co-first author.)

(5) Junwei Zeng*Hye Mee Joo*Bheemreddy RajiniJens P WrammertMark Y SangsterThandi M Onami. The generation of influenza-specific humoral responses is impaired in ST6Gal I-deficient mice. Journal of Immunology. 2009 Apr 15; 182(8):4721-7. (*co-first author.)