陈青云，博士毕业于香港大学李嘉诚医学院，免疫学专业，2020年以高层次人才引进入职广东省人民医院。主要从事肿瘤免疫和抗病毒免疫研究工作，研究成果以第一和通讯发表在Cancer Research、Journal of Autoimmunity、Journal of Immunology、Microbiology Spectrum等免疫学专业杂志上。主持国家自然科学基金2项、广东省自然科学基金面上项目1项、中国博士后科学基金1项。“珠江人才计划”海外青年人才引进计划（博士后项目）获得者。

研究内容：

利用临床标本、小鼠疾病模型，结合生物信息学、分子生物学、免疫学、表观遗传学等技术方法研究肿瘤微环境中的正向、负向免疫调控机制，宿主抗病毒感染机制，以及免疫相关疾病背后的分子机制等。

学术论著（第一及通讯）：

(1) Yunzhi Liu; Qishan Xu; Fan Deng; Zhuojun Zheng; Jialiang Luo; Ping Wang; Jia Zhou; Xiao Lu; Liyun Zhang; Zhengliang Chen; Qifan Zhang*; Qingyun Chen*; Daming Zuo*. HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway. Journal of Experimental & Clinical Cancer Research. 2023 Feb 1;42(1):38. (IF=12.658)

(2) Lei Li; Jialiang Luo; Zhengyumeng Zhu; Qishan Xu; Ping Wang; Bo Chang; Di Wang; Lu Yu; Xiao Lu; Jia Zhou; Daming Zuo*; Qingyun Chen*.SRA Suppresses Antiviral Innate Immune Response in Macrophages by Limiting TBK1 K63 Ubiquitination via Deubiquitinase USP15. Microbiology Spectrum. 2022 Dec 21;10(6):e0202822. (IF=9.043)

(3) Jialiang Luo; Lei Li; Zhengyumeng Zhu; Bo Chang; Fan Deng; Di Wang; Xiao Lu; Daming Zuo; Qingyun Chen*; Jia Zhou*. Fucoidan inhibits EGFR redistribution and potentiates sorafenib to overcome sorafenib-resistant hepatocellular carcinoma. Biomed Pharmacother.  2022 Oct;154:113602. (IF=7.419)

(4) Qingyun Chen*, Li L, Suo D. DNAse1L3 suppresses hepatocellular carcinoma growth via inhibiting complement autocrine effect. Neoplasma. 2021 Jul;68(4):683-691. (IF=3.409)

(5) Youyi Wang; Ping Wang; Qishan Xu; Lijun Dong; Yunzhi Liu; Yu Chen; Jia Zhou; Xiao Lu; Daming Zuo*; Qingyun Chen*. Inflammatory arthritis increases the susceptibility to acute immune-mediated hepatitis in mice through enhancing leptin expression in T cells. Molecular Immunology. 2021 Oct 19:140:97-105. (IF=4.174)

(6) Qingyun Chen; Yini Li; Xinyue Wang; Xu Zhang; Yi Hu; Lei Li; Daqin Suo; Ke Ni; Zhuo Li; Jiarong Zhan; Ting-ting Zeng; Yinghui Zhu; Yan Li; Lijia Ma*; Xinyuan Guan*. Tumor Fibroblast-Derived FGF2 Regulates Expression of SPRY1 in Esophageal Tumor-Infiltrating T Cells and Plays a Role in T-cell Exhaustion. Cancer Research. 2020 Dec 15;80(24):5583-5596. (IF=13.312)

(7) Qingyun Chen; Kun Wen; Aizhen Lv; Ming Liu; Ke Ni; Zheng Xiang; Yinping Liu; Wenwei Tu*. Human Vγ9Vδ2-T cells synergize CD4⁺ T follicular helper cells to produce influenza virus-specific antibody. Frontiers in Immunology. 2018 Apr 4;9:599. (IF=8.786)

(8) Qingyun Chen; Yinping Liu; Aizhen Lv; Ke Ni; Zheng Xiang; Kun Wen; Wenwei Tu*. Influenza virus infection exacerbates experimental autoimmune encephalomyelitis disease by promoting type I T cells infiltration into central nervous system. Journal of Autoimmunity. 2017 Feb; 77:1-10. (IF=14.511)

(9) Qingyun Chen^#; Hui Wang^#; Yang Liu^#; Yinjing Song; Lihua Lai; Quan Han; Xuetao Cao; Qingqing Wang*. Inducible microRNA-223 down-regulation promotes TLR-triggered IL-6 and IL-1β production in macrophages by targeting STAT3. PLoS One. 2012;7(8):e42971. (IF=3.752)

(10) Yang Liu^#; Qingyun Chen^#; Yinjing Song; Lihua Lai; Jianli Wang; Hai Yu; Xuetao Cao; Qingqing Wang*. MicroRNA-98 negatively regulates IL-10 production and endotoxin tolerance in macrophages after LPS stimulation. FEBS LETTERS. 2011 Jun 23;585(12):1963-8. (IF=3.864)

(11) Yang Liu^#; Lihua Lai^#; Qingyun Chen^#; Yinjing Song; Sheng Xu; Feng Ma; Xiaojian Wang; Jianli Wang; Hai Yu; Xuetao Cao; Qingqing Wang. MicroRNA-494 is required for the accumulation and functions of tumor-expanded myeloid-derived suppressor cells via targeting of PTEN. Journal of Immunology. 2012 Jun 1;188(11):5500-10. (IF=5.426)